I have one, but I didn't bother with the software. I just plugged the frequencies I wanted in the thing and was done with it. If you have the software and cable, it should be even more brain dead than usual. There's probably just a GUI front end you just start typing in frequencies. Have an idea in your head (or on a napkin) of how you want to set up the memory banks. I typically separate them by services. (EG, my main bank is local Fire/PD/EMT, the next one up from that is just for MSP, one bank I can switch on and off for ham stuff, etc. )
Also, don't bother using the headphone jack to plug in an external speaker..... the idiots that designed the thing decided to put an attenuator in line with the headphone jack... which is completely and utterly absurd... At least the speaker inside the unit is loud enough for most purposes.
-Mike