Yes. My wife is a very good shot and has shot a lot of different guns. She prefers a polymer Magpul handguard on her AR even though it's harder to mount stuff on, and it's not free float. She hates the feel of a quad rail even with rail guards on it. Her hands are just that much more sensitive I guess. She has been eyeing some lightweight tubular handguards recently though.
And I tried to rig her up with a Blue Force sling because I thought the single strap for tightening and releasing would be easier. She hated it because of the amount of pull force it requires vs. the VTAC. I had to swap it back out for her.
She also likes a lighter trigger. For a woman with less hand strength than a man, pulling a 6 lb trigger can feel like pulling a 12 lb trigger. I've got a JP Enterprise trigger on one of the rifles and she likes that, but hasn't made me put it on hers yet.
Oh, and she HATES malfunctions, especially when she's the only woman in a training class. I always load her up with the Federal stuff and I shoot the steel and polymer, just to minimize problems.
Now if I could just figure out how to shoot as good as she does.