I have Lyman's 50th, but I don't find it particularly useful. Only loading .45 ACP, and had relied on Hodgdon's website more (using Clays and Win 231). Published COAL seems almost irrelevant since cast 200 gr SWC are very COAL sensitive for proper feeding in my 1911. My only recommendation for using published data is to start with the starting loads and use with a chronograph. Work up the loads and watch for signs of high pressure in the spent cases. If trying to reach a specific velocity, such as trying to reach major power factor for the bullet's weight, work up the load until you have something that is equal or faster than the required velocity plus 200% of the standard deviation. Tweak from there to optimize accuracy.