I both like and dislike working from home. I didn't have much of a commute to begin with but going to 0 is much nicer. What I find to be the hardest is there are no breaks in the day. Before you had to give people time to walk from meeting to meeting, and my facility is pretty big, so sometimes there was a 10 minute walk between meetings. Now it's just click the X, click "Join Meeting Online" and you're into the next meeting. Being On for what is typically a 10 hour day is exhausting. No walking, no chitchat, no "I'll be late I have to swing by the coffee machine and then hit the head", just work. The only times I can actually get real work done is during lunch or in the evenings, which makes for even longer days.
I'm grateful to have a job that has pretty much worked seamlessly through all of this though.