Does anyone know of a portable water filtration system that filters out both Bacteria/microbes and harmful chemicals?
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Check out First Need portable filters from General Ecology, Inc. I've used mine in some nasty, mucky, bug filled water in the 100 Mile Wilderness (Maine AT) and on a 2 week treks in the southern Rockies. Not as compact or light as others but it's a serious filter that removes pretty much everything- bacteria, cysts, even viruses. Check the specs, but it should remove chemicals as well- it is tested by checking to see if it completely removes blue dye from water.
On one of two Rockies treks, about halfway through our 120 miles everyone else's MSR's and Katadyn's gave up the ghost and were either clogged or broken from trying to force water through clogged elements. The First Need filter was the only survivor and became our only source of purified water for several days. Conditions were near drought and the water sources at times really sucked- like barely a trickle of brown water in a stinky mudhole.
https://generalecology.com/images/files/pdf/200385A FNXLEspec1012.pdf
They have larger systems as well, though I have only used the portable one. It's not too complicated to backwash this filter if/when it requires backwashing. I highly recommend it.
Note: SEAGULL IV systems do not remove beneficial dissolved salts and essential minerals.
You just need carbon to filter chemicals - that's why dirt is such a good filter.