Hmmm. I've generally found H110/W296 to shoot rather cleanly, though I don't happen to shoot it in revolvers very much. It's more my go-to powder for the .357M and .44M Henry rifles. I may have shot less than 100 rounds of H110 reloads in my model 69, and about the same amount in my model 27, if that many. Normally in revolvers I shoot moderate loads using a non-magnum powder or some mid-range powder. I've had a stash of factory loads to shoot, dating back to when I stocked up before I started reloading, when I wanted full recoil. So my data on H110 in revolvers specifically might be a little on the thin side. I just don't remember seeing it. I was, however, getting those granules with Heavy Pistol. Also got some tiny ones with AA#7 recently.
I use 22.5gr in 44 magnum with the Zeros because the mid-22's gave me the tightest groups in my Henry BB Carbine. I don't think I have 22.5gr chrono'd specifically, but 22gr gave me 1526fps, 23gr 1620fps, and 24gr 1672gr, so I didn't think I was giving up too much in velocity, and the higher loads gave me larger groups. Took it up to 24.6gr but found nothing special there. YMMV.
I do use the Lee FCDs a lot, and they often seem to touch something or other before they're really down on the case mouth. If you just stop when they first touch, a half turn might do nothing at all. At least that's what happens to me. I always turn through initial contact until it's lightly snugged down using my fingertips only to turn it (not the sort of grip I'd use to torque a knurled nut down). Then I adjust it from there, starting with about 1/3rd of a turn. A half turn usually works out to what I want, at most 2/3. I doubt I've never gone a full turn from that point. That would be a lot.
BTW, just as a related aside here, the Lee FCD, stiff-ass GFL brass, and the .431 ZBC bullets are a bad combo--the sizing ring in the die struggles to get over the bullet. That can't be doing anything good. When I load those 240gr Zeros in GFL brass (which I sometimes do when I'm thinking about maybe not bringing my brass home), I crimp with the seating die.