1. If you enjoy the forum please consider supporting it by signing up for a NES Membership  The benefits pay for the membership many times over.

  2. Dismiss Notice

First Marijuana Overdoes Death Recorded

Discussion in 'Off-Topic' started by Zappa, Jun 11, 2019.

  1. Zappa

    Zappa Road Warrior NES Member

    Joined:
    May 14, 2008
    Messages:
    43,182
    Likes Received:
    13,196
    Location:
    Living Free In The 603
  2. kelton

    kelton NES Member

    Joined:
    May 5, 2012
    Messages:
    6,131
    Likes Received:
    8,666
    Location:
    counting flowers on the wall
  3. StevieP

    StevieP NES Member

    Joined:
    Apr 16, 2009
    Messages:
    7,980
    Likes Received:
    3,133
    Location:
    Gone to Carolina in my mind...
    Coroners aren't required to be doctors, as medical examiners are.

    Probably a political appointee
     
  4. Super99Z

    Super99Z NES Member

    Joined:
    Aug 30, 2010
    Messages:
    4,045
    Likes Received:
    2,838
    Location:
    South Shore
    Ban it! That will keep it out of the country!
     
  5. McReef

    McReef NES Member

    Joined:
    Mar 3, 2016
    Messages:
    373
    Likes Received:
    484
    Relaxed... all the way.
     
  6. 42!

    42! NES Life Member NES Member

    Joined:
    Apr 9, 2010
    Messages:
    5,645
    Likes Received:
    2,774
    I don't know about this case, but it makes sense that sooner or later someone will OD on THC.
    The historic "no one has ever ODed on weed" is accurate partly due to the way it is brought into the body, and both the lower potency of the past and probably the limits on how potent it can be made before it interferes with it being smoke-able.

    But now they are breeding higher and higher levels, and extracting it from the plant, which allows other means of delivery. Sooner or later someone is going to try injecting THC.

    So we may never see a Marijuana OD, but I'm betting there will be THC ODs.

    Nonetheless, I support legalizing all drugs and letting it sort itself out.
     
    Boris and dingbat like this.
  7. crazymjb

    crazymjb

    Joined:
    Mar 30, 2009
    Messages:
    9,764
    Likes Received:
    2,931
    Location:
    Green Eggs and...
    I'm sure plenty of regular pot smokers have died from complications due to long term use.
     
    AHM and jpk like this.
  8. Squire

    Squire

    Joined:
    Jul 5, 2009
    Messages:
    4,473
    Likes Received:
    2,031
    People should be free to do whatever they damn will please as long as it doesn't harm someone else.

    Being a drug addict or alcoholic with a family is a pretty shitty thing to do to your kids though...
     
    Wrench75 and Fixxah like this.
  9. crazymjb

    crazymjb

    Joined:
    Mar 30, 2009
    Messages:
    9,764
    Likes Received:
    2,931
    Location:
    Green Eggs and...
    Yeah but recreational use =/= addict
     
  10. Spanz

    Spanz NES Member

    Joined:
    Feb 25, 2009
    Messages:
    28,618
    Likes Received:
    13,524
    i think someone who has other diseases might be susceptible to dying while high. For instance, someone with severe diabetes might have very low blood sugar, not realize it, and end up in a coma. Or someone takes too many edibles, starts tripping balls, gets paranoid, and gets a heart attack....
     
    vicorjh likes this.
  11. cmcgraw2

    cmcgraw2 NES Member

    Joined:
    Dec 25, 2012
    Messages:
    1,171
    Likes Received:
    789
    Location:
    PRM
    Three out-of-towners, at least one elderly, hit the floor at a popular island restaurant last month. One of the women collapsed into the officer’s arms after he lightly tapped on her shoulder asking her to move so he could assist the other woman, the report states. "15 milligrams … THC … edible … all three… first time,” the woman told the officer.
    You're right some related coronary and it might be promoted as a fatal OD.

    Edibles blamed for Edgartown overdoses
     
  12. Racenet

    Racenet NES Member

    Joined:
    Aug 3, 2009
    Messages:
    2,269
    Likes Received:
    966
    Location:
    New Hampshire
    Not after eating the 16 bags of potato chips, in the munchie frenzy. [rofl]
     
    Jason Flare and Fixxah like this.
  13. Fixxah

    Fixxah NES Member

    Joined:
    May 1, 2008
    Messages:
    27,878
    Likes Received:
    6,690
    Location:
    Norwood mostly.
    Just dunk white toast in chocolate milk and the munchies will disappear after 12 slices.
     
  14. Spanz

    Spanz NES Member

    Joined:
    Feb 25, 2009
    Messages:
    28,618
    Likes Received:
    13,524
    in that case, maybe they just "fogot" to breath.

    :(
     
    Racenet likes this.
  15. vicorjh

    vicorjh NES Member

    Joined:
    Jan 9, 2015
    Messages:
    565
    Likes Received:
    187
    Caffeine has an LD50 of ~192 mg/kg
    Nicotine is ~60 mg/kg.
    Alcohol doesn't necessarily have an LD50, but if just .4 percent of your roughly 160 ounces of blood contains alcohol, you're in a bad situation.
    THC has an approximate LD50 range of ~1,260 - 666 mg/kg. At the lowest figure, a 175-pound man would have to consume greater than 53 grams of pure THC all at once. For commercially produced edibles, you would probably die from an overdose of salt (3,000 mg/kg) or sugar (1,100 mg/kg) before even coming close to the threshold for marijuana.
     
    Brewer, knoxy and mlaboss like this.
  16. 42!

    42! NES Life Member NES Member

    Joined:
    Apr 9, 2010
    Messages:
    5,645
    Likes Received:
    2,774
    You seem to have good information, maybe you can help with a couple points. At what rate does THC metabolize out of the system? What is the maximum concentration or TCH available (legally or illegally) in any form but in particular vape juice.
     
  17. dingbat

    dingbat

    Joined:
    Nov 2, 2008
    Messages:
    3,175
    Likes Received:
    1,323
    Location:
    North Taxolina
    Verbally abusing or beating your kids with your fist is a pretty shitty thing too.
     
    Jason Flare likes this.
  18. Chevy 2 65

    Chevy 2 65 NES Member

    Joined:
    Dec 29, 2013
    Messages:
    14,417
    Likes Received:
    5,121
    Location:
    Somewhere in the sands of time
  19. jkelly1229

    jkelly1229

    Joined:
    Nov 16, 2014
    Messages:
    4,021
    Likes Received:
    977

    Cmon doc we're not scientists
     
    dingbat and Jason Flare like this.
  20. Chevy 2 65

    Chevy 2 65 NES Member

    Joined:
    Dec 29, 2013
    Messages:
    14,417
    Likes Received:
    5,121
    Location:
    Somewhere in the sands of time
    Beer, whiskey, wine etc....is far more worse than weed. Move along
     
  21. vicorjh

    vicorjh NES Member

    Joined:
    Jan 9, 2015
    Messages:
    565
    Likes Received:
    187
    Oh, sorry. LD50 refers to the lethal dose where 50% of a population subject to that amount of substance would perish. This is usually determined through experimental trials on animals.
    Point was, for THC, it is a large amount.
    The more likely scenario is that this individual passed out, hit her head or something, and passed away from secondary cause. Or, something other than THC in the edibles contributed...
     
    AHM, dingbat, mlaboss and 1 other person like this.
  22. vicorjh

    vicorjh NES Member

    Joined:
    Jan 9, 2015
    Messages:
    565
    Likes Received:
    187
    I'll get back to you on what I can find for these. There is probably variability for both questions. Body fat and state, for instance.
     
  23. Pete85

    Pete85

    Joined:
    Jun 9, 2008
    Messages:
    10,635
    Likes Received:
    2,559
    I was just looking at that as well. To put those numbers into perspective, on the low end that would be 1.87oz of pure THC. Assuming pure THC has a similar density to water (I don't actually know its true density) you'd need to consume two shot glasses full of pure THC and have nearly perfect absorption into your system for there to be a 50% chance of it killing you. If she was vaping it, as the first article claimed, she'd have passed out long before she got anywhere near the LD50 dose. If you want to picture it in edibles, a Google search showed that a typical THC infused gummy bear has 10mg of THC. Some have more, some have less, but this seems to be the average. At that rate, you'd have to consume 5,300 gummy bears to reach the LD50 dose.

    I'd wager that if she didn't have THC in her system, they'd rule her death to be something like sudden cardiac arrest or speculate about some other possibilities, like she choked on an ice cube or something else that melted/evaporated and left little to no trace behind.
     
    dingbat and vicorjh like this.
  24. jkelly1229

    jkelly1229

    Joined:
    Nov 16, 2014
    Messages:
    4,021
    Likes Received:
    977
    Ahh gotcha that makes more sense
     
    vicorjh likes this.
  25. whatluck

    whatluck

    Joined:
    May 31, 2009
    Messages:
    7,957
    Likes Received:
    2,899
    Location:
    Braintree, MA
    Theres videos of people dabbing whole grams, basically freebasing pure thc. You tend to fall alseep before you clean up the drool at a tenth of that. Also, an LD50 dose would cost thousands. I bet if you abused other drugs you could trigger a siezure fall and hit your head.
     
    vicorjh likes this.
  26. Pete85

    Pete85

    Joined:
    Jun 9, 2008
    Messages:
    10,635
    Likes Received:
    2,559
    The second article states that she had 8.4 nanoliters of THC per milliliter of blood, or .0084 mg/liter. Since blood weighs about 1.06 kg/l, just in blood weight alone, that's less than 1/6000 of the LD50.
     
    drgrant and vicorjh like this.
  27. Hustler One

    Hustler One NES Member

    Joined:
    Dec 26, 2010
    Messages:
    1,069
    Likes Received:
    328
    Nonsense. She shouldnt have taken a drink from the mini-bar afterwards.
     
    dingbat likes this.
  28. JayMcB

    JayMcB NES Member

    Joined:
    Aug 8, 2011
    Messages:
    10,447
    Likes Received:
    5,174
    Location:
    Metro-Worst, assachusetts
    1.87 ounces....so 60 grams of shatter would get you there. But that's thousands of dollars. Literally pounds of weed to extract that much to shatter. But it could be ingested....
     
  29. knoxy

    knoxy NES Member

    Joined:
    Dec 2, 2011
    Messages:
    2,590
    Likes Received:
    860
    Location:
    Lunarville 7, Airlock 3
    Duuude, like, don't harsh the narrative Mang!
     
    vicorjh likes this.
  30. powerman

    powerman NES Member

    Joined:
    Sep 25, 2009
    Messages:
    1,068
    Likes Received:
    266
    Location:
    Eastern, MA
    its got the blue crystals
     
    JayMcB likes this.

Share This Page