If you're not reloading you are completely wasting your time with the 10mm platform. It's not worth touching at that point. If you are reloading (or intend on doing it in short order) it's pretty much a dream cartridge for it, because there are a lot of different loads and its pretty easy to deal with as long as you have brass, and it uses the same bullets as .40 S+W, plus you can load up things like 200s as well.
You can probably make "competent" SD ammo with things like 180 gr GDHP heads or similar from Remington.
A G20 or a G29 for a non reloader might as well be called "Holster and Safe dust collector" because that's exactly what it will do.
-Mike